Biocompatible Tough Ionogels with Reversible Supramolecular Adhesion
Jiaofeng Xiong1, Minzhi Duan2, Xiuyang Zou3, Shuna Gao1, Jiangna Guo1, Xiaowei Wang1, Qingning Li, Weizheng Li1（李维政）*, Xiaoliang Wang2（王晓亮）*, and Feng Yan*（严锋）
1Jiangsu Engineering Laboratory of Novel Functional Polymeric Materials, Jiangsu Key Laboratory of Advanced Negative Carbon Technologies, Suzhou Key Laboratory of Soft Material and New Energy, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
2School of Chemistry and ChemicalEngineering, Nanjing University, Nanjing 210023, China
3School of Chemistry and ChemicalEngineering, Huaiyin Normal University, Huaian 223300,China
J. Am. Chem. Soc. 2024, 146, 20, 13903–13913
ABSTRACT: Cohesive and interfacial adhesion energies aredifficult to balance to obtain reversible adhesives with both highmechanical strength and high adhesion strength, although variousmethods have been extensively investigated. Here, a biocompatiblecitric acid/L-(−)-carnitine (CAC)-based ionic liquid was devel-oped as a solvent to prepare tough and high adhesion strengthionogels for reversible engineered and biological adhesives. Theprepared ionogels exhibited good mechanical properties, includingtensile strength (14.4 MPa), Young’s modulus (48.1 MPa),toughness (115.2 MJ m−3), and high adhesion strength on theglass substrate (24.4 MPa). Furthermore, the ionogels can formmechanically matched tough adhesion at the interface of wetbiological tissues (interfacial toughness about 191 J m−2) and canbe detached by saline solution on demand, thus extending potential applications in various clinical scenarios such as wound adhesionand nondestructive transfer of organs.
链接：//pubs.acs.org/doi/10.1021/jacs.4c01758
