姓名：鲍晓光
职称：教授、博士生导师
部门：国际合作创新中心
联系方式：
地址：苏州市工业园区仁爱路199号；701号楼A504室
邮编：215123
Email：xgbao@maxbocai.com
学历及学术经历：
2002年毕业于上海交通大学化学化工学院，获学士学位；2007年毕业于中国科学院上海药物研究所，获博士学位。2007年至2012年先后在美国俄亥俄州立大学化学系和美国北德克萨斯大学化学系从事博士后研究工作；2012年8月到苏州大学博彩平台 工作。目前已经发表研究论文一百余篇，其中部分文章发表在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、ACS Catal.等杂志上，先后主持国家自然科学基金项目四项。
研究方向：
计算化学；物理有机化学；有机光催化；绿色化学
近五年代表性论文：
1. Kaifeng Wang and Xiaoguang Bao*
“Computational Insights into the Photoinduced Dimeric Gold-Catalyzed Divergent Dechloroalkylation of gem-Dichloroalkanes with Alkenes”
J. Am. Chem. Soc. 2024, 146, 7679–7689.
2. Rui Fu, Mengyu Xu, Yujing Wang, Xinxin Wu,* and Xiaoguang Bao*
“Organo-Photocatalytic Anti-Markovnikov Hydroamidation of Alkenes with Sulfonyl Azides: A Combined Experimental and Computational Study”
Angew. Chem. Int. Ed. 2024, 63, e202406069.
3. Yuzhu Peng, Yujing Wang, Kaifeng Wang, Qing Sun, and Xiaoguang Bao*
“Visible-Light Photocatalyzed C3–H Alkylation of 2H-Indazoles/Indoles with Sulfoxonium Ylides via Diversified Mechanistic Pathways”
ACS Catal. 2024, 14, 1193–1204.
4. Yi Zhang and Xiaoguang Bao*
“Computational Insights into the Zeolite-Supported Gold Nanocluster-Catalyzed Ethanol Dehydrogenation to Acetaldehyde”
Phys. Chem. Chem. Phys. 2024, 26, 9593–9600.
5. Youhao Wei, Zheng Wang, Kaifeng Wang, Jiang-Kai Qiu, Zhaoshan Wang, Haotian Li, Xiu Duan, Kai Guo, Xiaoguang Bao*, Xinxin Wu*
“Copper-Catalyzed Radical Allene C(sp2)-H Cyanation”
Angew. Chem. Int. Ed. 2024, 63, e202317132.
6. Kaifeng Wang and Xiaoguang Bao*
“Mechanistic Understanding of the Dual Gold and Photoredox-Catalyzed Thiosulfonylation of Alkynes and Enynes: A DFT Study”
Org. Chem. Front., 2023, 10, 2798–2807.
7. Qing Sun, Yuzhu Peng, Yujing Wang, and Xiaoguang Bao*
“Construction of α-Acyloxy Ketones via Photoredox-Catalyzed O−H Insertion of Sulfoxonium Ylides with Carboxylic Acids”
Org. Lett. 2023, 25, 6613−6617.
8. Zhicheng Yan, Yiyao Pan, Guofeng Jiao, Mengyu Xu, Dongguang Fan, Ziwei Hu, Jiarui Wu, Tao Chen, Miao Liu, Xiaoguang Bao*, Hengte Ke*, and Xingyue Ji*
“A Bioorthogonal Decaging Chemistry of N-Oxide and Silylborane for Prodrug Activation both In Vitro and In Vivo”
J. Am. Chem. Soc. 2023, 145, 24698-24706.
9. Zhanqun Liang, Kaifeng Wang, Qing Sun, Yuzhu Peng, and Xiaoguang Bao*
“Iron-Catalyzed Dual Decarboxylative Coupling of α-Amino Acids and Dioxazolones under Visible-Light to Access Amide Derivatives”
Chem. Commun. 2023, 59, 752–755.
10. Kaifeng Wang and Xiaoguang Bao*
“Computational Understanding on the Dual Gold and Photoredox-Catalyzed Regioselective Thiosulfonylation of Alkenes”
J. Org. Chem. 2023, 88, 1107–1112.
11. Yali Meng, Qinghao Sun, Tianjun Zhang, Jichao Zhang, Zhuoya Dong, Yanhang Ma, Zhangxiong Wu, Huifang Wang, Xiaoguang Bao*, Qiming Sun*, and Jihong Yu*
“Cobalt-Promoted Noble-Metal Catalysts for Efficient Hydrogen Generation from Ammonia Borane Hydrolysis”
J. Am. Chem. Soc. 2023, 145, 5486−5495.
12. Ran Liu, Kang Lv, and Xiaoguang Bao*
“Mechanistic Insights into the Enantioselective C(sp3)−H Acylation to Construct α-Amino Ketones via Photoredox and Ni(II) Dual Catalysis: A DFT Study”
Chem. Asian J. 2023, 18, e202201266.
13. Kang Lv and Xiaoguang Bao*
“Mechanistic Insights into Nickel- and Gold-Catalyzed Diastereoselective [4 + 2 + 1] Cycloadditions between Dienynes and Diazo Compounds: A DFT Study”
Org. Chem. Front. 2022, 9, 693–702.
14. Feng Jin, Xueli Wu, Kang Lv, and Xiaoguang Bao*
“Understanding Diversified Chemoseletivities in Rh2(II)-Catalyzed Intramolecular Annulation Reactions of Diazo and N-Sulfonyl-1,2,3-Triazole Compounds: A DFT Study”
Mol. Catal. 2022, 517, 112047.
15. Qing Sun and Xiaoguang Bao*
“Facile Preparation of Dihydro-1,4-benzothiazine Derivatives via Oxidative Ring-Expansion of 2-Aminobenzothiazoles with Olefins”
Chem. Commun. 2022, 58, 2216–2219.
16. Kang Lv, Xiaoguang Bao*
“Mechanistic Differences between Aryl Iodide Electrophiles and Pronucleophiles in Pd-Catalyzed Coupling with Cyclopropenes: a DFT Study”
Org. Chem. Front. 2022, 9, 5237–5245.
17. Shaofang Zhou, Tiantian Liu, Xiaoguang Bao*
“Direct Intermolecular C(sp3)–H Amidation with Dioxazolones via Synergistic Decatungstate Anion Photocatalysis and Nickel Catalysis: A Combined Experimental and Computational Study”
J. Catal. 2022, 415, 142–152.
18. Shaofang Zhou, Kang Lv, Rui Fu, Changlei Zhu, and Xiaoguang Bao*
“Nickel/Photoredox Dual Catalytic Cross-Coupling of Alkyl and Amidyl Radicals to Construct C(sp3)−N Bonds”
ACS Catal. 2021, 11, 5026−5034.
19. Rui Fu, Ran Liu, Kang Lv, Changlei Zhu, and Xiaoguang Bao*
“Silver-Catalyzed Desulfurizative Annulation of 1,2-Benzisothiazoles with Ynamides to Construct Multi-Substituted Isoquinolines”
Org. Chem. Front. 2021, 8, 5446–5453.
20. Zhanqun Liang, Kang Lv, Shaofang Zhou, Changlei Zhu, and Xiaoguang Bao*
“Visible-Light Photocatalytic Preparation of Alkenyl Thioethers from 1,2,3-Thiadiazoles and Hantzsch Esters: Synthetic and Mechanistic Investigations”
Org. Chem. Front. 2021, 8, 6499–6507. (HOT Article)
21. Kang Lv, Xiaoguang Bao*
“Mechanistic Insights into the Rh(I)-Catalyzed Transannulation of 1,2,3-Thiadiazoles with Alkenes, Alkynes, and Nitriles: Does the Intermediacy of α-Thiavinyl Rh-Carbenoid Play an Important Role?”
Org. Chem. Front. 2021, 8, 310–318. (HOT Article)
22. Luyao Kou, Ping Dai, and Xiaoguang Bao*
“Mechanistic Insights into the Rh(I)/Rh2(II)-Catalyzed Divergent Ring-Opening of Cyclopropenes: A Computational Study”
ChemCatChem. 2020, 12, 5656–5663. (VIP paper)
23. Kang Lv, Ping Dai, Xiaoguang Bao*
“Mechanistic Understanding of the Pd(0)-Catalyzed Coupling Cyclization of 1,2-Allenyl Ketones with Aryl Halides: A Computational Study”
ACS Catal. 2020, 10, 13202–13212.
24. Ke Gao, Luyao Kou, Rui Fu, Xiaoguang Bao*
“Synthesis of 2-(3-Arylallylidene)-3-oxindoles via Dirhodium(II)-Catalyzed Reaction of 3-Diazoindolin-2-imines with 1-Aryl-Substituted Allylic Alcohols and Computational Insights”
Adv. Synth. Catal. 2020, 362, 1292−1297.
25. Jiemin Ge, Xueli Wu and Xiaoguang Bao*
“Rhodium(II)-Catalyzed Annulation of N-sulfonyl-1,2,3-triazoles with 1,3,5-Triazinanes to Produce Octahydro-1H-purine Derivatives: A Combined Experimental and Computational Study”
Chem. Commun. 2019, 55, 6090–6093.
26. Si-Wen Yuan, Hui Han, Yan-Lin Li, Xueli Wu, Xiaoguang Bao,* Zheng-Yang Gu,* Ji-Bao Xia*
“Intermolecular C–H Amidation of (Hetero)arenes to Produce Amides through Rhodium-Catalyzed Carbonylation of Nitrene Intermediate”
Angew. Chem. Int. Ed. 2019, 58, 8887–8892.
27. Abosede Adejoke Ogunlana, Jianping Zou,* Xiaoguang Bao*
“Insights into the Mechanisms and Chemoselectivities of Amides in Rh(II)-Azavinylcarbene Involved Reactions: A Computational Study”
J. Org. Chem. 2019, 84, 8151–8159.
28. Abosede Adejoke Ogunlana, Xiaoguang Bao*
“Mechanistic Insights into the Gold(I)-Catalyzed Annulation of Propiolates with Isoxazoles: A DFT Study”
Chem. Commun. 2019, 55, 11127–11130.
29. Yu-Yang Xie, Zhi-Min Chen,* Hui-Yun Luo, Hui Shao, Yong-Qiang Tu,* Xiaoguang Bao,* Ren-Fei Cao, Shu-Yu Zhang, Jin-Miao Tian
“Lewis Base/Brønsted Acid Co-catalyzed Enantioselective Sulfenylation/Semipinacol Rearrangement of Di- and Trisubstituted Allylic Alcohols”
Angew. Chem. Int. Ed. 2019, 58, 12491–12496.
30. Xueli Wu and Xiaoguang Bao*
“Computational Insights into Different Chemoselectivities in Rh2(II)-Catalyzed N-aryl Nitrene and Analogous Rh2(II)/Cu(I)-Catalyzed Aryl-Substituted Carbene Involving Reactions”
Catal. Sci. Technol. 2019, 9, 1518–1527.
