Jian Han Li Zhang Yan Zhu Yongxiang Zheng Xiaolan Chen Zhi-Bin Huang Da-Qing ShiYingsheng Zhao
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University
Chem. Commun., 2016,52, 6903-6906
The first bidentate directing group assisted highly selective meta arylation of β-arylethylamine derivatives via palladium/norbornene catalysis is reported, and the range of aryl iodides for the oxalyl amide assisted meta-selective arylation reactions is broadest yet reported. This meta arylation also proceeds well with thiophene derivatives, giving the corresponding products in satisfactory yields. And three-step functionalization of arylethyloxalamide with three different functional groups is successfully performed.
链接：//pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC02384C#!divAbstract
