†,†,‡,‡,†,†,‡,‡, and† （万小兵）
† Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University
‡ Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University
J. Org. Chem., 2016, 81 (8), 3103–3111
An efficient synthesis of Z-perfluoroalkyl-substituted enones by a multicomponent reaction strategy has been described. A variety of elusive perfluoroalkylated enones are furnished under mild reaction conditions in good yields with unique chemo- and stereoselectivity. A sequence of radical-mediated Kornblum–DeLaMare reaction, Michael addition, and HF elimination is proposed for the mechanism.
链接：//pubs.acs.org/doi/abs/10.1021/acs.joc.5b02664
