Yaoyao Deng,a Erdong Li,a Xiaju Cheng,b Jing Zhu,a Shuanglong Lu,a Cuicui Ge(葛翠翠),*b Hongwei Gu*a (顾宏伟)and Yue Pan*a (潘越)
a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
b School for Radiological and Interdisciplinary Sciences (RAD-X) & Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University
Nanoscale, 2016,8, 3895-3899
The hybrid platinum@iron oxide core–shell nanorods with high biocompatibility were synthesized and applied for combined therapy. These hybrid nanorods exhibit a good photothermal effect on cancer cells upon irradiation with a NIR laser. Furthermore, due to the presence of a high atomic number element (platinum core), the hybrid nanorods show a synergistic effect between photothermal and radiation therapy. Therefore, the as-prepared core–shell nanorods could play an important role in facilitating synergistic therapy between photothermal and radiation therapy to achieve better therapeutic efficacy.
链接://pubs.rsc.org/en/content/articlelanding/2016/nr/c5nr09102k#!divAbstract