†, †, ‡, †（邱丽华）, and †‡（徐新芳）
† Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University
‡ Jinghua Anti-Cancer Pharmaceutical Engineering Center, Nantong
ACS Catal., 2016, 6 (2), 1024–1027
A copper-catalyzed novel carbene/alkyne metathesis cascade reaction with alkyne-tethered diazo compounds is described. The whole transformation features a dual-functionalization of alkyne to install one C═N and one C═C bond on each carbon with azide and diazo groups, respectively, in one reaction, which represents a practical synthetic alternative to the multisubstituted 4-carboxyl quinoline derivatives and with most of them in high to excellent yields.
链接：//pubs.acs.org/doi/abs/10.1021/acscatal.5b02648
