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徐小平副教授与纪顺俊教授合作在Org. Lett.上发表研究论文
Palladium-Catalyzed Cyclization of Alkenes with Organohalides

Xue-Qiang Chu, Dan Liu, Zhen-Hua Xing, Xiao-Ping Xu*(徐小平), and Shun-Jun Ji*(纪顺俊)

 

Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University

 

Org. Lett., 2016, 18 (4), 776–779

 

A palladium-catalyzed tandem C–Br/C–H functionalization and cyclization of alkenes with organohalides is reported. This reaction provides an operationally simple method for the synthesis of various fluorene, pyrroloindole, and benzoxazine derivatives, which are useful pharmaceutical framework and photoelectronic devices. Two new C–C/O bonds, a quaternary carbon center and a new ring, are simultaneously formed in this one-pot reaction.

 

 

链接://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b00035