Kun Guoa, Xiaolan Chena, Jingyu Zhangb, Yingsheng Zhao*a （赵应声）
a Key Laboratory of Organic Synthesis, Jiangsu Province College of Chemistry
Chemical Engineering and Materials Science, Soochow University
Suzhou 215123 (P. R. China)
b College of Physics Optoelectronics and Energy & Collaborative Innovation Center
Suzhou Nano Science and Technology, Soochow University，Suzhou 215006 (P. R. China)
Chem. Eur. J. 2015, 21, 17474 – 17478
Biaryls, which contained a benzyloxy motif, were directly constructed through a ligand-promoted Pd(II) -catalyzed ortho-arylation of masked aromatic alcohols. A variety of acetoxime ethers could be coupled with a diverse range of arylboronic acid pinocol esters, giving direct access to bioactive biaryls in modest to good yield. Not only could acetoxime be subsequently removed without a separation, functionalized hydroxylamine derivatives could also be obtained.
链接：//www.pubfacts.com/detail/26449857/PalladiumII-Catalyzed-Acetoxime-Directed-ortho-Arylation-of-Aromatic-Alcohols
