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汪顺义副教授与纪顺俊教授合作在J. Org. Chem.发表研究论文

Palladium-Catalyzed Regioselective C–H Acylation of Biaryl-2-amines

Zhong-Jian Cai,   Chao Yang,   Shun-Yi Wang*(汪顺义)  and   Shun-Jun Ji*(纪顺俊)  

 

Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China

J. Org. Chem. 2015, 80, 7928–7936

 

A palladium-catalyzed efficient C–H acylation reaction of biaryl-2-amines and aromatic aldehydes is developed. This dehydrogenative cross-coupling protocol could furnish monoacylation and diacylation products in moderate to good yields with a broad substrate scope and good regioselectivity.

 

链接:

//pubs.acs.org/doi/abs/10.1021/acs.joc.5b00962