博彩平台

Synthesis of heterodimer radionuclide nanoparticles for magnetic resonance and single-photon emission computed tomography dual-modality imaging

Jing Zhu,^a   Bin Zhang,^b   Jian Tian,^c   Jiaqing Wang^a,   Yu Chong^c,   Xin Wang^d,   Yaoyao Deng^a,   Minghua Tang^e,   Yonggang Li^d,   Cuicui Ge^*c(葛翠翠),   Yue Pan^*a(潘越)  and   Hongwei Gu^*a(顾宏伟)  

^a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, China

^b Department of Nuclear Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China

^c School for Radiological and Interdisciplinary Sciences (RAD-X) & Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, China

^d Department of Radiology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China

^e Analysis and Testing Center, Soochow University, Suzhou, China

Nanoscale 2015, 7, 3392-3395

We report a facile synthesis of bifunctional Fe₃O₄-Ag¹²⁵I heterodimers for use as dual-modality imaging agents in magnetic resonance (MR) and single-photon emission computed tomography (SPECT). We introduced ¹²⁵I, which is a clinically used radioisotope, as a SPECT reporter, into Fe₃O₄-Ag heterodimer nanoparticles to provide a new type of bifunctional contrast agent for MRI and SPECT imaging.

链接：

//pubs.rsc.org/en/Content/ArticleLanding/2015/NR/c4nr07255c