Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University, Suzhou 215123 (China)
Chem. Eur. J. 2015, 20, 17198 – 17206
A metal-free direct alkylation of simple carbonyl compounds (ketones, esters, and amides) with α,α-diaryl allylic alcohols is described. The protocol provides facile access to highly functionalized dicarbonyl ketones by a radical addition/1,2-aryl migration cascade. The regioselectivity of the reaction was precisely controlled by the nature of the carbonyl compound.
链接：
//onlinelibrary.wiley.com/doi/10.1002/chem.201404463/abstract
