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陈高健副教授与陈红教授合作在Chem. Commun.发表研究论文

Visible light induced fast synthesis of protein–polymer conjugates: controllable polymerization and protein activity

Xin Li,a   Lei Wang,a   Gaojian Chen,*ab (陈高健)  David M. Haddletonc and   Hong Chen*a (陈红)

 

a The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, P. R. China

b Center for Soft Condensed Matter Physics and Interdisciplinary Research, Soochow University, Suzhou, P. R. China

c Department of Chemistry, University of Warwick, Coventry, UK

 

Chem. Commun. 2014, 50, 6506-6508

 

Herein visible light is used to induce RAFT polymerization from protein for preparing protein–polymer conjugates at ambient temperature. Polymerization is fast and can be conveniently controlled with irradiation time. By site-specific polymerization of NIPAm to protein, the protein activity is maintained and in certain cases it presents an efficient on–off-switchable property.

链接:

//pubs.rsc.org/en/content/articlelanding/cc/2014/c4cc02277g#!divAbstract