Synthesis of Isatins by I2/TBHP Mediated Oxidation of Indoles
You Zi , Zhong-Jian Cai , Shun-Yi Wang *(汪顺义), and Shun-Jun Ji *(纪顺俊)
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China
Org. Lett. 2014, 16, 3094–3097
An I2/TBHP mediated oxidation of commercially available indoles has been developed, which affords isatins in moderate to good yields.
链接: //pubs.acs.org/doi/abs/10.1021/ol501203q