Iodine-Catalyzed Cascade Formal [3 + 3] Cycloaddition Reaction of Indolyl Alcohol Derivatives with Enaminones: Constructions of Functionalized Spirodihydrocarbolines
Wen-Juan Hao , Shun-Yi Wang *(汪顺义), and Shun-Jun Ji *（纪顺俊）
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
ACS Catal. 2013, 3, 2501–2504.
A simple and practical method for the synthesis of spirodihydrocarboline derivatives from indolyl alcohol derivatives with enaminones via an iodine-catalyzed cascade formal [3 + 3] cycloaddition reaction has been developed. The reaction afforded the desired products under mild conditions in moderate to good yields with excellent regioselectivities.
链接： //pubs.acs.org/doi/abs/10.1021/cs400703u
