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顾宏伟教授与潘越副教授合作在Nanoscale发表研究论文

Synthesis of Au–Fe3O4 heterostructured nanoparticles for in vivo computed tomography and magnetic resonance dual model imaging

Jing Zhu,a   Yinjie Lu,a   Yonggang Li,b   Jiang Jiang,c   Liang Cheng,d   Zhuang Liu,d   Liang Guo,b   Yue Pan*a (潘越) and   Hongwei Gu*a  (顾宏伟)

 

a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, China
b Department of Radiology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China

c i-Lab and Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, China

d Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Institute of Functional Nano & Soft Materials Laboratory (FUNSOM), Soochow University, Suzhou, China

 

Nanoscale 2014, 6, 199-202

 

Water-soluble Au–Fe3O4 heterostructured nanoparticles with high biocompatibility were synthesized and applied as a dual modality contrast agent. These nanoparticles present strong CT/MRI contrast enhancement in a rabbit model. Low concentrations of Au–Fe3O4 were found to obtain a similar effect to high concentrations of a commercial iodine agent in the CT image.

 

 

链接: //pubs.rsc.org/en/Content/ArticleLanding/2013/NR/C3NR04730J#!divAbstract