a Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Suzhou 215123, P. R. China
Polym. Chem. 2013, 5, 14-24
The review focuses on the combination of surface topography and surface chemical modification with the grafting of polymer chains to develop optimal material interfaces for biological and biomedical applications. Understanding how surface chemistry and topography correlate with the interfacial properties and biological functions of a material is important for the development of biomaterials. Synergies between these two properties are known to exist, but have not been exploited extensively for biomaterial design. Preliminary studies suggest that the combination of surface topography and chemistry may not only enhance surface properties, but may also give biological properties that are opposite to those of the corresponding smooth surface, and even other unexpected biological properties. This review summarizes some recent studies in this area, mostly carried out in our own laboratory, as examples to illustrate how synergistic properties and functions may be obtained by combining surface topography with
链接：//pubs.rsc.org/en/content/articlelanding/2013/py/c3py00739a#!divAbstract
