Isocyanide-Based Multicomponent Reactions: Catalyst-Free Stereoselective 3 Construction of Polycyclic Spiroindolines
Xiang Wang(王翔), Shun-Yi Wang(汪顺义),* and Shun-Jun Ji (纪顺俊) *
Org. Lett. 2013, 15, 1954-1957.
A novel catalyst-free one-pot tandem reaction for the stereoselective construction of polycyclic spiroindolines was developed. This method offers a straightforward access to structurally diverse polycyclic spiroindoline derivatives in high yields (up to 90%) with excellent levels of diastereoselectivity. 
