报告题目：Measuring of Particle-Surface Interactions in Aqueous Environments with Total Internal Reflection Microscopy
报告人：魏涛（香港中文大学）
报告时间：2013年12月13日（周五）上午9：30
报告地点：独墅湖校区907号楼1445报告室
欢迎广大师生踊跃参加。
报告内容：
The non-covalent intermolecular forces, such as van der Waals, electrostatic, and hydrophobic/hydrophilic interactions, have played an essential role in determining the association, aggregation, adhesion and sedimentation processes of colloidal particles, surfactant micelles, macromolecules in solutions, or biological systems. They are normally in the range of tens of femtonewton to piconewton that is challenging and difficult to be directly measured by common techniques. In this talk, I will discuss recent advances in the development of non-intrusive optical technique of total internal reflection microscopy (TIRM) for studying the interactions between a single, colloidal particle and a flat surface. I will begin with a brief overview of quantitative optical microscopy measurements of particle-surface interactions, and then show recent advances associated with TIRM for measuring kT-scale interactions between a single particle and surface modified with polymers, polyelectrolyte brushes or nanoparticles. Lastly, I will demonstrate that TIRM can also be employed to directly measure the biological interactions, such as protein-carbohydrate and protein-protein interactions, which provides a basic to understand interactions in biologically relevant systems, including drug particles and viruses.
魏涛副教授简介：
To Ngai was born in Fujian province of China in 1976. He received his B.S. in chemistry at the Chinese University of Hong Kong in 1999. In 2003, he obtained his Ph.D. in chemistry in CUHK under the supervision of Professor Chi Wu. He moved to BASF (Ludwigshafen, Germany) in 2003; first as a postdoctoral fellow for one year, then as the chemist in polymer physics division. In July 2005, he went to Prof. Lodge’s group in the Chemistry Department of the University of Minnesota, working on polymer blending. He returned Hong Kong in 2006 and joined the Chemistry Department of the Chinese University of Hong Kong as a research assistant professor and is now an associate professor. Currently, his research interests center on the designing, synthesizing and measuring interactions between polymers, particles and soft materials.
