报告题目:Cardiovascular Tissue Engineering: “PRIME” the Environment
报告人：Prof. Dr. Erik Suuronen, Director of Laboratory Research for the Division of Cardiac Surgery, University of Ottawa Heart Institute, Canada
报告时间：6月10日上午10:00-11:00
报告地点：909-1445
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报告摘要：
Biomaterials are emerging as promising regenerative therapies for treating cardiovascular disease. Our research group has been developing injectable hydrogels for the delivery of therapeutic cells and regenerative cytokines. Materials are also being designed as stand-alone therapies that can enhance the host regenerative responses. All these materials will be presented and discussed. We are also investigating the mechanisms responsible for the therapeutic benefits observed with our matrices. Imaging modalities and molecular and cellular analyses have identified properties of the materials that confer their therapeutic potential and how the matrices interact with the cells to induce tissue regeneration. While these strategies to regenerate tissue are attractive, cardiac regeneration following an ischemic event is impaired by the production of toxic by-products. Different approaches we are studying to understand and minimize these inhibitory effects will also be discussed.
报告人简介：
Dr. Erik J. Suuronen is a Principal Investigator and the Director of Laboratory Research for the Division of Cardiac Surgery at the University of Ottawa Heart Institute. Dr. Suuronen received his B.Sc. in Biology in 1996 and his Ph.D. in Cellular and Molecular Medicine in 2004, both from the University of Ottawa, followed by a post-doctorate at the Ottawa Heart Institute.
Dr. Suuronen’s research interest is in tissue engineering and cell-based therapeutic approaches for the treatment of cardiovascular injury and disease. This includes the investigation of biomaterial scaffolds and stem/progenitor cell transplantation for promoting cardiac regeneration and improving heart function. He is also investigating how the body’s own stem cells respond when the heart is damaged or when a tissue becomes ischemic, and how to enhance this natural repair response. In addition, the Suuronen lab is studying regenerative approaches for the treatment of diabetes and associated cardiovascular complications. Dr. Suuronen has published over 50 research articles and book chapters. In 2007, he received the Young Investigator Award (first runner-up) from the Canadian Cardiovascular Society. In 2009, his work on biomaterials designed to recruit the body’s own stem cells received international media coverage. He has served as a reviewer or committee member for several major granting agencies world-wide.
